Baggrund
Every year several million people experience a physical trauma on a global scale. When treating these patients, international trauma guidelines are followed, which includes oxygen treatment. Some studies suggest that liberal oxygen treatment might be harmful.
Purpose
This project aims to investigate the long-term consequences, including quality of life and mortality, of a restrictive versus a liberal oxygen treatment for trauma patients.
Method
A multicenter trial (www.traumox2.org) randomized trauma patients to receive either a restrictive oxygen strategy or a liberal oxygen strategy for eight hours after trauma. In this follow-up study, these patients are contacted at six and twelve months after trauma. This contact will include completion of two questionnaires (GOSE and EQ-5D-5L), which will evaluate the quality of life of the patients and the results of which will be compared between the two groups. Furthermore, the two groups will be compared according to 1-year mortality. Finally, we will focus on patients with traumatic brain injury since these are known to be a special subgroup of trauma patients.
Cooperation
All four Danish Helicopter Emergency Medical Services participate in the TRAUMOX2 trial, being a cooperation between the Department of Anaesthesiology/Trauma Center at Rigshospitalet, the Danish Air Ambulance, Department of Anaesthesiology and Intensive Care at Odense University Hospital, Department of Anaesthesiology at Aarhus University Hospital, and physician staffed mobile units prehospital in Region Midt, Region Syd, and Region Hovedstaden. Moreover, the study is an international cooperation with centers in Europe including the Netherlands and Switzerland.